Yes, but somebody here (mathman, or 260Remguy?) commented once about the single lugged bolt 340 not being a swell platform for the hot .225, and that's why Savage dropped it after a brief foray?
The .225 was intended to be a rimmed replacement for .22-250-class cartridges. An answer to a question seldom asked by any but single shot riflemen.
Johno- yes, but the 99 can handle both rimless and rimmed cartridges. The .225 rim is smaller than a .30-30 rim but rimmed nonetheless, while all the other dimensions are compatible with basic .30-30 case dimensions.
If I were going the .225 route I would cut to the chase and build a .219 Donaldson Wasp on a suitable single shot action and call it a day. It's what the cool kids did 60 years ago, don'tcha know?!