I have used the 220 grains in 30-06s and the 200s in my 300H&Hs.
In the 30-06 I use IMR3031 for the M-1 Garand (yes it works-- and the port pressure is low) and IMR4350 in my M95 Browning. Both with the 220 grain.
In my 300 H&H I use H4831 with the 200 grains.
I have killed 5 elk with the two 30-06s named above using the 220s and several deer, as well as one bear.
With my 300H&Hs (one M70 Winchester and one Mauser) I have used the 200 grain Partitions and have killed antelope,(1) deer (7) and (3) elk. To be honest, I have not seen any difference in how the 2 bullets worked on any game yet.
All were excellent, and no shot left a bullet in the body so I can't speak to the retained weight, but I don't really care either. Clear through is the objective, and in both the 30-06s and the 300s all gave me exits. All gave good sized diameters wounds and when bone was hit they just cut them off and kept going.
I like them and see them as the "Gold Standard" which I compare all other bullets to.
