180 grain Barnes.

Took my .308 on 3 trips and shot everything from Steenbok to Zebra, Gembok, and Kudu. I took my .300 Jarrett with 165 Grain Accubonds on my last trip to Tanzania and felt a little under-gunned with the 165s. I would take 180 grain Barnes next time. It's Africa, you likely aren't going to have a lot of shots over 150 yards. Ignore the velocity comments on here and go with a 180 grain Barnes. It'll penetrate enough and good trackers will have no issues finding a well-hit animal.