6x45 and 6TCU. I have found both to perform over what most figure they should. A wide variety and types of bullets. At the reduced speed compared to say 243, SOME of the varmint bullets perform well on deer sized critters. I use 55-80 grain bullets for my needs.

The selection of 25 bullets is some what sparse. 25-20 and 25-35, then right to the 257 or 25-06. Often times the bullets that do work well in the 25x45 are hard to find. Use the 6.8 case and the will open some options on bullet performance.