I use a spreadsheet. I use different tabs for different cartridges. I record the bullet, number of rounds, powder & charge, primer, brass, seating depth, date loaded, date fired and temperature, velocity average for each charge, extreme velocity spread, and group size. The beauty of it is that I can easily sort data to see what loads have turned in the best accuracy over long periods of time, since I've done it this way since about 2005. Example:
Hornady 154-grain SP 3 56.5 / H4831 Fed 210M -0.030 01/06/08 01/15/08 1.70"
3 57.0 / H4831 Fed 210M -0.030 01/06/08 01/15/08 1.12"
3 57.5 / H4831 Fed 210M -0.030 01/06/08 01/15/08 .50"
3 58.0 / H4831 Fed 210M -0.030 01/06/08 01/15/08 .83
3 58.5 / H4831 Fed 210M -0.030 01/06/08 01/15/08 1.75"
(I didn't record velocities when I tested this load.)