Once upon a time I handloaded for all the centerfire rifles I owned with IMR4895, IMR4350 and H4831. They worked fine for everything from the .223 Remington to the .338 Winchester Magnum. (The only reason for both IMR4350 and H4831 was one usually resulted in a little better accuracy. Probably wouldn't bother today--but mil-surp H4831 was still cheap back then!)
Would much rather do something like that than use one powder.
