For a few years I used 100 gr Nosler BTs over IMR 4064. Worked great. Then I decided to see if the 120’s were better on deer and hogs, so I shot them over R17. Both loads were very accurate. As to effectiveness on game, I honestly can’t say that the 120’s were more effective. Both bullets worked very well. I get exits from deer with both bullets. I get exits on hogs sometimes. I’m presently using the 120’s.
