I've seen good results with light-for-caliber offerings when using mono-bullets pushed hard. They were great on bone, great on leaving exits, and still fairly good on lungs, primarily due to the speed.
100gr E-Tip at 3350fps in 25cal
100gr TTSX at 3200fps in 6.5mm
110gr TTSX at 3,200fps in 7mm
130gr TSX at 3350 in 30cal
I've also used or seen used lighter cup/cores at 3,300 or so in 7mmRM and 300WM. They were much more devastating than the mono bullets, but they also shot up a lot of meat. Lots of DRT shots with anything in the chest cavity, but I'd not want them for an angling-away shot.
Now that I think about it, I've also used lighter mono-bullets at more moderate speeds to keep down recoil. The 120gr 7mmTTSX, 130gr .30cal TTSX, and 185gr .338cal TTSX have worked well enough at speeds from 2700 to 2900. Not as decisive as the fast monos listed above, but totally adequate in terms of damage, blood trails, and ability to take on bad shot angles.
