For game up to about 500 pounds, the Nosler Partition or Accubond in the 165 grain weight is unbeatable. For elk and larger I like the same, but in 200 or 220 grain weights.
But there is nothing wrong with the 180 grain either for a one-size fits all in all the 300 mags.
Get the bullet out the other side in a fairly straight line and you have done all you can do with any 300 mag and any bullet.
The bullet is a tool to make the hole. It's the hole that kills, not the bullet.
