I was shooting H380 in my 22-250's but wasn't happy with how it behaved when it got hot on the prairie dog fields, it does some pretty wild stuff when it gets hot. I experimented with several powders and settled on AR-Comp. It gives me good velocities, accuracy, temp stability, and it was widely available at the time which was about five years ago. I laid in a bunch of it and still have 16 lbs in the locker if I remember right.
I like AR-Comp a lot, it's a very versatile powder with a lot of uses and it's consistent which is something I can't say for a lot of others.
Metering isn't something I pay much attention to because I've got two chargemasters side by side I use to weigh everything.
