A rag and some carburetor cleaner was enough to take the moly off of some Fail Safes. These were an odd lot and didn't have the Lubaloy coating. I was mixing bullets so cleaned them. If you are not mixing bullets I would try them coated, I would probably knock the carbon out of the barrel at the half way point of 250 rounds. With R-16 you shouldn't get much copper build up at all. If you have a chronograph I would load back up to the velocity you were getting before if I could do it with a half to a full grain of powder more. But I would stop there even if I was not back up to the previous velocity.