I'm guessing that if he's close enough for spray you are supper. 12 gauge slugs or heavy rifle bullets at the first sign of trouble might work. I've never had a hostile encounter with a bear but I've seen them cover a good bit of ground pretty fast. I'm betting he can make 15 or 20 feet per second.
A grizzly bears speed is 35 MPH. Phil Shoemaker stopped a grizzly bear charge and killed the bear with a 9mm shooting 147 Buffalo Bore's +P Outdoorsman Ammo
Yeah, but Phil can shoot!
If you take the time it takes, it takes less time. --Pat Parelli
American by birth; Alaskan by choice. --ironbender