I’ve never killed a leopard but I have killed many animals with a 308 and the majority of those animals fell to a 150 hornady. I would have absolute faith in that combination. As someone else mentioned I would hang the best/brightest scope I could find on it. Good luck on your hunt.
Interesting comment about the best/brightest scope. I’m actually changing out the 4-14 Zeiss conquest I have on my .338 to a Leupold VX5HD 2-10 for that very reason. 30mm tube with the fire dot reticle should be a great scope for leopard hunting, as well as everything else. Nothing wrong with the Zeiss, I just wanted a 30mm tube and love the fire dot.
