In our house, our go to "not sure what I'm gonna get into" rifle/cartridge combo is the .300 win with 200 gr. accubonds.

Many deer and elk. Several bear and antelope. And 2 NM oryx....near or far. It has done a great job, with minimal tracking, and no lost animals. Although, 1 of the oryx took a little "convincing", that he was dead!

Andy3