I have 35s on my 3500 and will go back to 33s when i need new tires. I want the extra bed rail clearance when pulling the 5r and i am hoping that the MPG will increase both loaded and empty. I am fairly easy on the skinny pedal and get 18-19 on the hiway. I would like to be 20ish like my old 12 vlv. Most all aftermarket tranny builders will not warranty a build if the tire size is over 35".