I've got both & it depends upon how you load the 45-70. With factory loads suitable for the older rifles it's not too bad. If you load it full bore then you can get it to almost 458 Win Mag levels and it's a bitch.

The 45-70 can be anything from mild to wild or anywhere in between. If you stand on it in a modern rifle with heavier bullets it'll rattle your teeth worse than the 338 ever will.