I shot a decent size bear using a 350 gn soft point PMC ammo. I don't think it's available anymore.
I have taken 3 deer using both Federal & Winchester factory with 300gn bullet
and a coyote. Only bullet recovered was from the coyote, only because it hit a tree branch behind him and deflected into the ground. I just happen to see the bark peeled off of the pine branch and a small divit in the ground below it.