I use the Hornady 300 gr HP Interlock bullet in my .45-70 Guide Gun and I've killed 1 deer and 4 bear with it all one shot each. The farthest any of those went was a bear that went about 30 yards before piling up. It is a devastating bullet..
If I were to use my .45-70 on something more substantial like moose I would likely opt for the 350 gr RN from Hornady.
Last edited by ClemB; 12/04/22.
