For 20 years living in British Columbia I ran one load in my only centerfire rifle, a 30-06:

165 grain Sierra, 56 grains IMR 4350, CCI Magnum primers, one batch of Federal brass that I loaded over and over with a Lee Loader and an Ohaus 5-0-5 scale. That load would group about 5/8 inch all day long, any number of rounds. I didn’t have a chronograph, and went for accuracy over velocity. This “middle range charge” was the most accurate of those tested from 53 to 59 grains. It killed a pile of game.