Several years ago I lusted for a nice 22LR. I searched for an action to do a build but never came up with the right one. I bought a Cooper Western Classic and love it. I decided a 22 mag would be the next step and fun to shoot short range prairie dogs, and other vermin. I got a CZ 457 and it's scary accurate. It just doesn't move me aesthetically however and another Cooper moved in next to the 22. Evolution can be a cruel thing and the 17 HMR beckoned to me. I bought a Browning T bolt with the medium heavy barrel. It's a great gun, accurate and I like the 10 round magazine. I don't care for the crappy stock and plastic trigger guard. The web can be a cruel and financially destructive place. I found another Cooper in 17 HMR. Out of all of these my favorite is the Cooper Custom Classic 22 mag. I'll probably get the Browning restocked at some point and the CZ will probably go up for sale.
I have a 22 Hornet as well but the rimfires are much handier to use especially in confined spaces.