This problem has ABSOLUTELY NOTHING to do with Chamber a round and EVERYTHING to do with extracting a fired case. Once again if you run only factory rounds or mild loads with Horny brass you may or may not have as bad a problem, it can take 3- 6 firings on brass to show up
depending on your load.
Okay, now I get this magic phenomenon!
Suspected this might be the so-called "problem," partly because unlike some handloaders I have yet to exceed published 6.5 PRC data. But apparently some might, which I have found to cause similar problems in some other cartridges. That extra 50-100 fps must matter a lot. Surprise!
Have never had any problem extracting fired cases in my rifle, just tight chambering a few after a couple firings. As with many other hunting rounds I have marked those rounds for use for zero-checking, instead of hunting.