The biggest challenge is finding a powder that provides a quiet suppressed report. I find Hogdgon Trail Boss and no filler to be the ticket. Other powders I have tried, while rendering subsonic velocities, were nonetheless loud when fired.
T.S.
I use Unique for my cast&coated subsonic.45-70 loads. Would like to try Trail Boss but it doesn’t seem available anymore.
As to the OPs question, if your can is only rated to .45 Colt then that’s what I’d get unless you want to buy another can. I love shooting subs in my Marlin 1895 Trapper but my can (Hybrid 46) is rated for high pressure rounds.
