I had a combination license and was elk hunting when a mule deer buck presented himself @ 30yds.. A 275gr. bullet from my .338WM behind his ear instantly lobotomized him, didn't even blink just went straight down. There was a fist sized hole in the opposite side of his skull and the cranium was completely devoid of brain tissue. Hit a whitetail doe just below the spine with a 12ga. slug, she acted as though she had been struck by lightning.