Have to agree with IMR-4350 and H-4350 in the .30-06/165 or 180's . Right now, my Ruger #1 works verrry nice with 57.0gr H-4350& 180 Horn. or Partitions. However, I've been using Hunter in another '06[Ruger Mk2] with 165 Horn& Part. and that shoots very ,very good! Those three powders are all you need for your .30-06. Good luck. Rifletom