Collect the Colt, shoot the Smiths (N frame, that is). The Python is over rated, IMO, compared to similar vintage (and cheaper) Smith and Wessons. I've had and shot several; the only Colts in my corral have AQHA papers.
I have only pulled the trigger on one Python, but have owned and shot several S&W. The double action on the Python was much nicer than the Smiths. The Smith ranged from the early sixties to the eighties. They may be better now.