The most common set up I see that goes to Africa from Canon;
500 f4 IS
100-400L
24-70 2.8.
I'd love to have a 500 f4 myself but right now that's an apples and oranges deal. A used 300 2.8 MKI in great shape is running right around $3,600 give or take $100.
A 500 is a solid 2k more used and a few pounds heavier.
I'd venture a guess that by this time next year both of these in MK1 form will be selling for a good bit more.
Either way If I was only taking one lens it wouldn't be a prime.
