Don't think you could tell the difference under 400 yds. the 300WSM should be better beyond, however. Shot my WY elk last yr with a 300WSM at 439 yds. Shot was broadside lung hit and 180gr Nosler passed right thru. Haven't chro'ed it yet, but I load 64.5gr of 4350. Shoots 1 1/2" at 200 yds.
John