I don't own a bow, as such I have never bow hunted. Both my brothers have quite a bit. That said, my father gave me good advice when he first took me to the field. Granted it was with a rifle, but I think the principle still applies here.
"Never, EVER, shoot at a deer."
"Dad, if I don't shoot at hit how will we get it!?"
"Again, don't you dare EVER shoot at a deer. Shoot at a SPOT on the deer."
Basically, know exactly where your bullet/arrow is going to impact before you pull the trigger/release the string.
Those that KNOW what their projectile is going to do can call certain shots a low risk, where those that THINK they know what it will do have to agree that those shots are indeed high risk...... for THEM.
Take that any way you like.