Yea, as along as you put the round where it belongs, a .22 will take out most anything. If you look in the new Speer #14 Manual there is a picture of a guy with a big Kat using the 200 Speer JHP...that is a great penetration and hole cutter. Like a jacketed Keith bullet. This guys cougar was a BIG one also...

Don't think you are wrong about the 210 RSP being a very decent bullet. I know lots of people who have killed all manner of game with them. One of the guys over on the S&W Forums killed I think 23 deer in Alaska with his model 57 using the factory load...

If you want a bullet that will expand at all velocities use a 210 Speer Gold Dot HP...

950-1250-1400 fps...

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And being a plated bullet it will never come apart. I fired one out of a .405 Winchester and hit a 2.5 gallon water jug...the bullet turned completely inside out but held together...don't know what I was thinking as the bullet was sitting there next to the jug, I looked at it and then threw it up on the bank...

Bob

If you can not deal with reality, reality will deal with you....