To be honest, I dont think it makes a big difference. You can tweak your gun and ammo to make it sub MOA. Some people will shoot 200gr .338 for Caribou and .250gr .338 for Moose. They will experiment with with partitions, accubonds, ect. Where I live its not that critical. If I can hit an 8 inch target at 250y 4 out of 5 shots I am good to go because almost all my shots are under 200y.
By a couple boxes of different ammo. Take it to the range and see what performes the best then go with it. I know that if I hit a mmose with a 150+gr round in the heart/lung area he wont be taking to many steps, especially if he didnt see me firts.
Of course there may be some long range antelope hunters that may have a valid argument for me.
