I would not worry about loading or driving it, but unloading it without bending, scratching, breaking or torquing something would be the exception rather than the rule.
FWIW, I run a 1,600 lb tote for deliveries in my Tacoma all the time, no problem. Rent it out and never had a pickup with problems hauling it.
Well, except the woman with the 16 year old son who refused to strap it in and then hit the brakes hard. She needed a new rear window......
