I shot a small hog between the eyes 3 times with 40fmj Winchester Super X out of my single six. She dropped at the shot but was back up dazed within 10 seconds, the last time she went down I ran up and put one in the ear canal for the win. This was about an 80# live weight hog distance was about 15 yards. Based on that I wouldn't recommend it for shooting hogs, though I'd still poke one with it if I had nothing else with me.
For a feed truck rifle that I might shoot pigeons and rabbits with as well as the target of opportunity coyote or bobcat, I'd say okay. For a dedicated predator rifle I'd be looking at a centerfire.
