My brother in law has killed a bunch of yotes with the 22 WMR Federal 50 gr load at his place in Mass but very few went down within sight. He's been using CCI Maxi-Mags lately and reports similar performance. A centerfire is out of the question where he lives.
In CT we're limited to 22 LR on state land and I've killed a few with Velocitors but they usually run off a ways. The only one I've killed on the spot I shot in the neck at about 20 yards.
I'd rather use my 222 Rem but the private land spots I have now are small so you might get to set-up once or twice and then you have to drive to another spot.
