My knowledge of Peacemaker clones is limited, but you can often modify ammunition to suit your new gun. Modifying the bullet weight, as Poodleshooter mentioned, is one change that you should consider.
Choose your new gun according to the guidelines you have for quality, price and "fit". Buy several varieties (brands and bullet weights) of commercial ammunition. Take some paper targets and go shooting. Probably you won't have issues, but each gun is a new experience in the behavior of inanimate objects, making predictions of accuracy, or lack thereof, very difficult.
If your POA doesn't match your POI, there are LOTS of things you can change. The targets will be important pieces of data, so burn some powder and tell us your tale!