I'm a believer in shooting until they are on the ground. Neck shot at close range gets what you would expect but so does a spine shot at 350 yards - they hit the dirt right now. Lung shots that are fatal may not have much reaction or may trigger a death run. I have hit and killed them on a dead run but they take more than one fatal shot to stop moving.

Lung shot with a high neck finisher is not a bad plan how much adrenalin is in an elks system makes a big difference in what they do when hit..