Crimson Tide,
I have an Accusport 5.5" Bisley Blackhawk just like yours. I use the 45-270-SAA loaded with 13.5 grains of HS6 for about 1100fps. Great deer load. To the OP, I have used a 629 with 240grain XTPs, and a 7.5" Redhawk with 225 grain Speer half jacket SWC hollowpoint to kill deer in Ohio. Any 200 plus grain load that you can hit a paper plate with at 40 yards should smoke a whitetail.
Ron
