I don't hunt waterfowl, so a Browning A5 Light Twelve gets it all done for me. My new one needs tubes added, since it's a fixed full choke.
My first A5 was a 26" IC plain barrrel, and I killed a lot of upland game as well as my first two deer with it.
For truly everything, a 12ga O/U with tubes and sights or a red dot clamped to the rib as needed for slugs would really be all I need to hunt anywhere I'm likely to go these days.