Terrific as a mule deer, pronghorn & coyote rifle!
I generally handload, and have taken game from 20 - 400+ yards, typically with one shot.
Mine is a Rem 700 CDL, with a 6x Leupold. Pretty much perfect setup for the hunting I enjoy.
What surprised me, after I got my .25-06, was learning how many people I know who use the cartridge for elk!
Regards, Guy