Seems to me that a low powered variable or a nice tough fixed power scope is the way to go with a .375, but that's just my preference.

I've got a 1.5-5x Leupold on mine now. In the past it's had a 2.5x Leupold, and also an older 2-7x Redfield. I've used it on bears from 10-15 feet, out to over 300 yards.

Regards, Guy