I feel like the 1.75-6x32 Varix-III on my .375 is nearly perfect. It had a 1.5-5x20 on it for a while, it it was moved to a quick handling 35 Whelen. I can't fathom of a situation that a 375 works welll for that a 6x32 isn't "enough". The 1.5-5x was great too,