The 375 has more range potential than most safari calibers, so i think the scope should take advantage of that. A 3-9, 2.5-8, something in that range allows 300 yard shots, but can still handle close-range opportunities.
I agree Biebs. I don't know if it's just my eyes, but a 3x or 4x just isn't going to cut it at "400" yards as some of these guys can shoot that far with ease with those scopes. Not me. The x hair would blot out the said critter at that distance and I'd be wishing and praying to hit somewhere, hopefully hair. That's just not the way I hunt or try to place shots. I ran a Zeiss conquest 3.5-10x44 on mine and it will work near and far set up that way. That scope is still running like a champ too, but now it's on my 7 pound 338. We'll see if the recoil of that rifle finally puts it down. Only time and rounds downrange will tell.