I have shot several eland. Most with a .375 HH as I prefer to get them on the ground quickly. I have shot one with a .300WM, it died quickly. The PH's I have hunted with all prefer the hunter use a .375HH as it does the job with no apologies. A 6.5 Creedmore would be fine on everything up to wildebeest/kudu/eland/zebra. If you are spending your money on an African hunt, do what the PH suggests. He has the experience, you do not.