It can be done but wouldn't be my first choice especially in brush country.
When you hang a mature eland bull next to a mature cape buffalo bull the eland is larger.
I witnessed a mature eland bull soak up three rapid shots in the heart lungs zone from a 6.5 SAUM pushing 140 gr. Northforks at 260 yards with no reaction to the impacts.
He died but I remember thinking a larger caliber with more energy would be a good thing.
