AS was stated before, the difference in reaction of a buff is quite a bit more when hit with a 416 of any type than a 375 of any ilk. Simply putting a lot more WHAP onto the target. A better stopper in a bad situation. That said, the recoil is noticably different and since your PH will likely have a stopping rifle for follow up shots and crisis intervention a 375 is a very versatile and useful tool worldwide and is a VERY popular choice among clients (Vs. PH's) hunting any of the big 5. The 45's are more of the same but drop way down in versatility and way up - again - in Recoil and as such are not really as popular with hunters and really should not be, in my opinion.

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About 2016 team "R" candidates "We definitely need a crew with a sack of balls the size of hot water bottles, bloviated estrogen leaking feel-gooders need not apply." Gunner 500