Hi All
My opinion as a guide/outfitter over here is that you need to balance bullet weight to animal size as well as shooter ability. I have many hunters coming through that use 30-06's as well as 300 Win mag of mine and have found the best combo is a 165 Nosler accubond in 30-06 and a 180 Accubond in 300. Velocity is similar in the 2 options, but recoil is way less in the 30-06. I also have the option of Suppressors on one of each caliber that are more often than not chosen by the youngsters and lady hunters (Minimal recoil and very little noise)
I believe that the 180 grainer is probably the best choice all round, but my rifles shoot the above best and as we all know , placement is king