378 wby, quickest, hardest ever in a 9.5 lb gun........but then again, I've never shot a 460 wby.
MM
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FWIW, I have read in a few different places that the 378's felt recoil is worse than that of a 460Wby.
Now, I don't know if that is true,as I have never fired the 460 but I found it to be noteworthy all the same.