I took a Remington 700 CDL in 35 Whelen to South Africa this this year shooting old Speer 250 grain Spitzer over IMR 4064. Killed great.

I had a shot at a bull kudu that apparently hit an unseen branch on the way there. I shot him a second time quartering away were he dropped. Examination showed four entry wounds and one perfectly mushroomed bullet under the offside skin and two wounds to the lungs. So even using 40 year old soft bullets and the first shot breaking into at least three pieces, it still inflicted a mortal wound. I think this illustrates what is meant by "it's hard to make a bad choice".