The best deer rifle to me is one that's optimum for the circumstances. I pack at least two with me for back up anyway.
For the forests up North I chose the .358 Win. as I wanted to take running shots and the extra effect of that round provides superior "shot placement".
For open spaces I have some rifles with more range.
Of late I have been using a custom 30-06 because I like the rifle.
The one on the right is an 264 M70 Westerner.