I have shot 3 deer with a 243. Two have been in the heart lung areas and penetrated leaving a good sized exit wound. The third went thru both shoulders and ended up a perfect mushroom that I could feel under the hide of the off shoulder. If I recall it was a corelokt and weighed about 68 grs as a reference for the coreloct thread. All three deer were recovered within 10 ft of where they were shot. Ranges were from 25-200 yds. Don't make this harder than it needs to be. A good 100gr bullet will do fine though as someone mentioned the boattails do seem to shed their cores more than flat based bullets in my observation. In my experiences above two were coreloct and one was a hornady flat base.