My family has killed a lot of large whitetails and hogs with the 100g Interlock with the load of 42.3g of H4350 and a win primer, it is very accurate. More than a few 200 lb whitetails have fallen to this load at ranges of 300 yards(Kansas) and a few in Nebraska.

Personally, I prefer the flat base version, but the rest of the family shoot boat tails.